Pengaruh Ekstrak Batang Dan Daun Pakis Sayur (Diplazium Esculentum) Terhadap Kadar Hemoglobin, Hematokrit dan Jumlah Eritrosit Pada Tikus Putih Jantan yang Disuntikkan Natrium Nitrit (NaNO2)

Authors

  • Geby Sashmita Program Studi Teknologi Laboratorium Medik, Universitas Bali Internasional
  • I Gusti Putu Agus Ferry Sutrisna Putra Program Studi Teknologi Laboratorium Medik, Universitas Bali Internasional
  • Ni Putu Widayanti Program Studi Teknologi Laboratorium Medik, Universitas Bali Internasional

Keywords:

Anemia, Erythrocyte Amount, Hematocrit, Hemoglobin, Vegetable Fern

Abstract

Background: Anemia is a decrease in hemoglobin level, hematocrit value and the number of erythrocytes in the body due to a lack of iron intake in the body. One plant that is rich in iron is vegetable ferns (diplazium esculentum). This research was conducted at the Animal Unit Laboratory of the Faculty of Medicine, Udayana University. Objective: To determine the effect of vegetable ferns and stem extracts on hemoglobin levels, hematocrit values and the number of erythrocytes. Method: This study uses true experimental design. Results: The results of this study prove that stem fern extract and vegetable ferns can increase hemoglobin levels, hematocrit values and the number of erythrocytes in experimental male rats with a dose of 0.18 grams, 0.36 grams and 0.72 grams. Conclusion: There was a significant effect on male white mice with anemia treatment after being given stem and vegetable fern leaf extract, where the administration of vegetable fern extracts and ferns with a dose of 0.72 grams resulted in an increase in hemoglobin levels of 52.07%, a hematocrit value of 32, 91% and the number of erythrocytes is 29.41%.

References

Mollet, Inês G., Dilipkumar Patel, Fatima S. Govani, Adam Giess, Koralia Paschalaki, Manikandan Periyasamy, Elaine C. Lidington, et al. 2016. “Low dose iron treatments induce a DNA damage response in human endothelial cells within minutes.” PLoS ONE. https://doi.org/10.1371/journal.pone.0147990.

Sashmita, Geby. 2014. “Perbedaan Kadar Hemoglobin Darah Hewan Coba Tikus Putih Jantan (rattus novergicus) Strain Wistar Sebelum dan Setelah Pemebrian Filtrate Tanaman Pakis Sayur (diplazium esculentum).” Politeknik Kesehatan Kemenkes Mataram.

Sembiring, Asmitra, Masitta Tanjung, dan Dan Emita Sabri. 2013. “Pengaruh Ekstrak Segar Daun Rosela (Hibiscus sabdariffa L.) Terhadap Jumlah Eritrosit dan Kadar Hemoglobin Mencit Jantan (Mus musculus L.) Anemia Strain Ddw Melalui Induksi Natrium Nitrit (NaNO2).” Saintia Biologi 1 (2): 60–65. https://www.neliti.com/ publications/221147/pengaruh-ekstrak-segar-daun-rosela-hibiscus-sabdariffa-l-terhadap-jumlah-eritros.

WHO. 2011. “Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System.” Geneva, Switzerland: World Health Organization. https://www.who.int/vmnis/indicators/haemoglobin/en/.

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Published

2020-08-31